Translating Basic Research into Clinical Applications: Malaria Research at an NIH Lab
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منابع مشابه
Translating Basic Research into Clinical Applications: Malaria Research at an NIH Lab
Malaria is a deadly disease caused by Plasmodium parasites with active transmission in nearly 100 countries. The parasites infect approximately 200 million people each year, killing over a half million patients. Although there is no active transmission in the United States, the US government and military have active research programs on malaria, including drug and vaccine development and variou...
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Basic or pure research advances fundamental knowledge about the world and generates new ideas, principles, and theories, which, while not always immediately usable, form the basis of progress and development in different fields and industries, even starting new ones. For example, computers could not exist without research in mathematical logics and solid state physics over a century ago, while ...
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There is a pressing need to make patient safety research more relevant to clinicians and decisionmakers. The RE-AIM framework of Reach, Effectiveness, Adoption, Implementation, and Maintenance is one approach investigators can use to assess a study’s potential for translation from research to clinical practice. In this paper, we show how the RE-AIM approach is being used to evaluate a pharmacy ...
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BACKGROUND Although research participation is essential for clinical investigation, few quantitative outcome measures exist to assess participants' experiences. To address this, we developed and deployed a survey at 15 NIH-supported clinical research centers to assess participant-centered outcomes; we report responses from 4,961 participants. METHODS Survey questions addressed core aspects of...
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The human body is more than the sum of its organs. Yet for hundredsof years,medicine andmedical research have divvied up the totality of the person into diseases that are organ specific and characterized largely by their phenotypic presentation. These divisions are also reflected in the organization of academic medical centers and pharmaceutical research and development and even permeate the fu...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2015
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1005190